3-CMC

Parameter Specification
Chemical Name 3-Chloromethcathinone
Common Abbreviation 3-CMC
IUPAC Name 1-(3-chlorophenyl)-2-(methylamino)-1-propanone
Chemical Class Synthetic cathinone (β-keto amphetamine)
Molecular Formula C₁₀H₁₂ClNO
Molecular Weight ~213.66 g/mol
CAS Number 160743-62-4
Appearance White to off-white crystalline powder
Odor Slight or none
Purity (typical) ≥ 98% (analytical standard grade)
Salt Form Commonly supplied as HCl salt
Solubility Soluble in water, ethanol, and polar organic solvents
Stability Stable under dry, cool, and dark conditions
Storage Conditions Store sealed at 2–8 °C; protect from moisture and light
Analytical Methods GC-MS, LC-MS, HPLC, NMR
Intended Use Laboratory and analytical research only
Pharmacological Category CNS stimulant (monoamine reuptake inhibitor/releaser)
Medical Use None approved
Toxicological Note Associated with neurotoxicity, cardiotoxicity, and systemic toxicity
Regulatory Status Controlled or monitored substance in many jurisdictions

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3-CMC (3-Chloromethcathinone; IUPAC: 1-(3-chlorophenyl)-2-(methylamino)-1-propanone) is a synthetic cathinone stimulant from the β-keto amphetamine family. Structurally it is a ring-substituted cathinone with a chlorine atom at the meta position of the phenyl ring, making it analogous to other designer stimulants such as 3-MMC and methcathinone. The compound typically appears as a white to off-white crystalline solid or powder.

Pharmacology and Effects:
Like other cathinones, 3-CMC is believed to increase extracellular levels of monoamine neurotransmitters (dopamine, norepinephrine, and serotonin) by inhibiting reuptake and promoting release. This mechanism produces stimulant and euphoric effects including increased energy, alertness, elevated mood, and sociability.

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